Kira8 (AMG-18)

Catalog No.: A18641
mono-selective IRE1α inhibitor
Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Grouped product items
Product Name Price Stock Qty
Kira8 (AMG-18) 5mg
$200.00
In stock
Kira8 (AMG-18) 10mg
$320.00
In stock
Kira8 (AMG-18) 50mg
$1,000.00
In stock
Kira8 (AMG-18) 100mg
$1,480.00
In stock
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Biological Activity
Discription Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Product Information
Catalog Num A18641
Formula C31H29ClN6O3S
Molecular Weight 601.12
CAS Number 1630086-20-2
SMILES O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O
Synonyms AMG 18, AMG18
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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