KL-1

Catalog No.: A18418
SEC inhibitor
KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
Grouped product items
Product Name Price Stock Qty
KL-1 1mg
$60.00
In stock
KL-1 5mg
$280.00
In stock
KL-1 10mg
$460.00
In stock
KL-1 50mg
$680.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
Product Information
Catalog Num A18418
Formula C18H16ClNO4
Molecular Weight 345.78
CAS Number 900308-84-1
SMILES O=C(NC1=CC(Cl)=CC=C1C)C(CC(C2=CC=CC(OC)=C2)=O)=O
Synonyms KL1; KL 1; KL-1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 64 mg/mL (185.08 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.92 mL 144.6 mL 289.2 mL
0.5 mM 5.78 mL 28.92 mL 57.84 mL
1 mM 2.89 mL 14.46 mL 28.92 mL
5 mM 0.58 mL 2.89 mL 5.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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