KPT 9274 (ATG-019)
PAK4/NAMPT Inhibitor
Important Notice: For research use only. We do not sell to patients.
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PAK4/NAMPT Inhibitor
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | KPT 9274 ( ATG-019) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay. |
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Catalog Num | A15506 |
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Formula | C35H29F3N4O3 |
Molecular Weight | 610.63 |
CAS Number | 1643913-93-2 |
SMILES | FC1=CC=C(C2=CC(C3=CC=C(C(N4CCC(F)(F)CC4)=O)C=C3)=CC5=C2OC(C/N=C(O)/C([H])=C([H])/C6=NC(N)=CC=C6)=C5)C=C1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 85 mg/mL (139.2 mM) | |
Water | Insoluble | ||
Ethanol | 85 mg/mL (139.2 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 16.38 mL | 81.88 mL | 163.77 mL |
0.5 mM | 3.28 mL | 16.38 mL | 32.75 mL |
1 mM | 1.64 mL | 8.19 mL | 16.38 mL |
5 mM | 0.33 mL | 1.64 mL | 3.28 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2