LY3214996
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | LY3214996 is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines. | ||
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Catalog Num | A16843 |
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Formula | C22H27N7O2S |
Molecular Weight | 453.56 |
CAS Number | 1951483-29-6 |
SMILES | CC(N(CCN1CCOCC1)C2=O)(C)C3=C2C=C(S3)C4=CC=NC(NC5=CC=NN5C)=N4 |
Synonyms | LY 3214996, LY-3214996 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 24 mg/mL (52.91 mM) | |
Water | Insoluble | ||
Ethanol | 14 mg/mL (30.86 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.05 mL | 110.24 mL | 220.48 mL |
0.5 mM | 4.41 mL | 22.05 mL | 44.1 mL |
1 mM | 2.2 mL | 11.02 mL | 22.05 mL |
5 mM | 0.44 mL | 2.2 mL | 4.41 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2