Lomerizine dihydrochloride

Catalog No.: A16599

Calcium Channel /TRP5 antagonist

Lomerizine dihydrochloride is a antagonist at L-type and T-type Ca 2+ channels and TRp5 channels used to treat migraines and vertigo.
Grouped product items
Product Name Price Stock Qty
Lomerizine dihydrochloride 50mg
$60.00
In stock
Lomerizine dihydrochloride 100mg
$100.00
In stock
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Biological Activity
Discription Lomerizine dihydrochloride is a antagonist at L-type and T-type Ca 2+ channels and TRp5 channels used to treat migraines and vertigo.
Targets
Target Value
Product Information
Catalog Num A16599
Formula C27H32Cl2F2N2O3
Molecular Weight 541.46
CAS Number 101477-54-7
SMILES COC1=CC=C(CN2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)C(OC)=C1OC.[H]Cl.[H]Cl
Synonyms B 2796, B2796, B-2796, Lomerizine HCl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 87 mg/mL (160.67 mM)
Water Insoluble
Ethanol Warmed: 45 mg/mL (83.1 mM)
In vivo 2% DMSO+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.47 mL 92.34 mL 184.69 mL
0.5 mM 3.69 mL 18.47 mL 36.94 mL
1 mM 1.85 mL 9.23 mL 18.47 mL
5 mM 0.37 mL 1.85 mL 3.69 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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