PAT-1251 Hydrochloride

Catalog No.: A21969
LOXL2 inhibitor
PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively).
Grouped product items
Product Name Price Stock Qty
PAT-1251 Hydrochloride 1mg
$320.00
In stock
PAT-1251 Hydrochloride 5mg
$960.00
In stock
PAT-1251 Hydrochloride 10mg
$1,600.00
In stock
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Biological Activity
Discription PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively).
Product Information
Catalog Num A21969
Formula C18H18ClF4N3O3
Molecular Weight 435.8
CAS Number 2098884-53-6
SMILES O=C(C1=CC=CC(OC2=NC(C(F)(F)F)=CC(CN)=C2)=C1)N3C[C@@H](F)[C@H](O)C3.Cl
Synonyms PAT 1251, PAT1251
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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