Pico145

Catalog No.: A13344
TRPC1/4/5 channels inhibitor
Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
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Product Name Price Stock Qty
Pico145 5mg
$270.00
In stock
Pico145 10mg
$465.00
In stock
Pico145 50mg
$1,380.00
In stock
Pico145 100mg
$2,760.00
In stock
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Biological Activity
Discription Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
Product Information
Catalog Num A13344
Formula C23H20ClF3N4O5
Molecular Weight 524.88
CAS Number 1628287-16-0
SMILES O=C1C2=C(N=C(OC3=CC=CC(OC(F)(F)F)=C3)N2CC4=CC=C(Cl)C=C4)N(C)C(N1CCCO)=O
Synonyms HC-608, HC608, HC 608, Pico-145, Pico 145
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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