SNX-5422 Mesylate

Catalog No.: A21512
Hsp90 inhibitor
SNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM.
Grouped product items
Product Name Price Stock Qty
SNX-5422 Mesylate 5mg
$162.00
In stock
SNX-5422 Mesylate 10mg
$279.00
In stock
SNX-5422 Mesylate 50mg
$828.00
In stock
SNX-5422 Mesylate 100mg
$1,656.00
In stock
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Biological Activity
Discription SNX-5422 Mesylate (PF-04929113 Mesylate), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her-2 degradation, with an IC50 of 37?nM.
Product Information
Catalog Num A21512
Formula C26H34F3N5O7S
Molecular Weight 617.64
CAS Number 1173111-67-5
SMILES CS(=O)(O)=O.O=C1CC(C)(C)CC2=C1C(C(F)(F)F)=NN2C3=CC=C(C(N[C@@H]4CC[C@@H](OC(CN)=O)CC4)=C3)C(N)=O
Synonyms PF-04929113 (Mesylate), PF04929113,PF-04929113
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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