Sorafenib

Catalog No.: A17857

Raf/VEGFR3 inhibitor

Sorafenib (Bay 43-9006) is a potent, orally active multikinase inhibitor with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Grouped product items
Product Name Price Stock Qty
Sorafenib 100mg
$54.00
In stock
Sorafenib 500mg
$162.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription Sorafenib (Bay 43-9006) is a potent, orally active multikinase inhibitor with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Targets
Target Value
Product Information
Catalog Num A17857
Formula C21H16ClF3N4O3
Molecular Weight 464.83
CAS Number 284461-73-0
SMILES O=C(NC(C=C1)=CC=C1OC2=CC(C(NC)=O)=NC=C2)NC3=CC=C(Cl)C(C(F)(F)F)=C3
Synonyms Bay 43-9006, Bay-43-9006, Bay43-9006
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 59 mg/mL (126.92 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+45%PEG400+50%H2O 0.35 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.51 mL 107.57 mL 215.13 mL
0.5 mM 4.3 mL 21.51 mL 43.03 mL
1 mM 2.15 mL 10.76 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy Sorafenib | Sorafenib Supplier | purchase Sorafenib | Sorafenib cost | Sorafenib manufacturer | order Sorafenib | Sorafenib distributor | buy 284461-73-0 | 284461-73-0 Supplier | purchase 284461-73-0 | 284461-73-0 cost | 284461-73-0 manufacturer | order 284461-73-0 | 284461-73-0 distributor