Sparsentan

Catalog No.: A20879
angiotensin II and endothelin A receptor antagonist
Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Sparsentan 5mg
$135.00
In stock
Sparsentan 10mg
$233.00
In stock
Sparsentan 50mg
$690.00
In stock
Sparsentan 100mg
$1,380.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
Product Information
Catalog Num A20879
Formula C32H40N4O5S
Molecular Weight 592.75
CAS Number 254740-64-2
SMILES O=S(C1=CC=CC=C1C2=CC=C(CN3C(CCCC)=NC4(CCCC4)C3=O)C=C2COCC)(NC5=NOC(C)=C5C)=O
Synonyms RE-021, RE021, RE 021; DARA-a
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 93 mg/mL (156.89 mM)
Water Insoluble
Ethanol 37 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.87 mL 84.35 mL 168.71 mL
0.5 mM 3.37 mL 16.87 mL 33.74 mL
1 mM 1.69 mL 8.44 mL 16.87 mL
5 mM 0.34 mL 1.69 mL 3.37 mL
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