TAK-659 hydrochloride

Catalog No.: A21885
Syk inhibitor
TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM.
Grouped product items
Product Name Price Stock Qty
TAK-659 hydrochloride 2mg
$81.00
In stock
TAK-659 hydrochloride 5mg
$162.00
In stock
TAK-659 hydrochloride 10mg
$315.00
In stock
TAK-659 hydrochloride 50mg
$927.00
In stock
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Biological Activity
Discription TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM.
Product Information
Catalog Num A21885
Formula C17H22ClFN6O
Molecular Weight 380.85
CAS Number 1952251-28-3
SMILES FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Insoluble
Water Warmed: 3 mg/mL (7.88 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.26 mL 131.29 mL 262.57 mL
0.5 mM 5.25 mL 26.26 mL 52.51 mL
1 mM 2.63 mL 13.13 mL 26.26 mL
5 mM 0.53 mL 2.63 mL 5.25 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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