Tolcapone

Catalog No.: A20966
COMT inhibitor
Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor.
Grouped product items
Product Name Price Stock Qty
Tolcapone 10mg
$54.00
In stock
Tolcapone 25mg
$108.00
In stock
Tolcapone 50mg
$186.00
In stock
Tolcapone 100mg
$318.00
In stock
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Biological Activity
Discription Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor.
Product Information
Catalog Num A20966
Formula C14H11NO5
Molecular Weight 273.24
CAS Number 134308-13-7
SMILES O=C(C1=CC(O)=C(O)C([N+]([O-])=O)=C1)C2=CC=C(C)C=C2
Synonyms Ro 40-7592, Ro40-7592, Ro-40-7592
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 53 mg/mL (193.96 mM)
Water Insoluble
Ethanol 53 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.6 mL 182.99 mL 365.98 mL
0.5 mM 7.32 mL 36.6 mL 73.2 mL
1 mM 3.66 mL 18.3 mL 36.6 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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