Tonapofylline

Catalog No.: A21328
adenosine A1 receptor antagonist
Tonapofylline (BG 9928) is an orally active and selective adenosine A1 receptor antagonist with a Ki of 7.4 nM for human adenosine A1 receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold selectivity versus human adenosine A2B receptor and is used in development for the treatment of heart failure.
Grouped product items
Product Name Price Stock Qty
Tonapofylline 5mg
$160.00
In stock
Tonapofylline 10mg
$260.00
In stock
Tonapofylline 50mg
$960.00
In stock
Tonapofylline 100mg
$1,520.00
In stock
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Biological Activity
Discription Tonapofylline (BG 9928) is an orally active and selective adenosine A1 receptor antagonist with a Ki of 7.4 nM for human adenosine A1 receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold selectivity versus human adenosine A2B receptor and is used in development for the treatment of heart failure.
Product Information
Catalog Num A21328
Formula C22H32N4O4
Molecular Weight 416.51
CAS Number 340021-17-2
SMILES O=C(O)CCC1(CC2)CCC2(C(N3)=NC(N(CCC)C(N4CCC)=O)=C3C4=O)CC1
Synonyms BG 9928
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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