WNK463

Catalog No.: A16205
pan-WNK-kinase inhibitor
WNK463 is an orally bioavailable pan-WNK-kinase inhibitor.
Grouped product items
Product Name Price Stock Qty
WNK463 1mg
$90.00
In stock
WNK463 5mg
$160.00
In stock
WNK463 10mg
$240.00
In stock
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Bulk Discount
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's WNK463 has been cited by 1 publications
  • Lu DC, .et al. , Pflugers Arch, 2019, Dec;471(11-12):1539-1549 PMID: 31729557
  • Biological Activity
    Discription WNK463 is an orally bioavailable pan-WNK-kinase inhibitor.
    Targets
    Target Value
    Product Information
    Catalog Num A16205
    Formula C21H24F3N7O2
    Molecular Weight 463.46
    CAS Number 2012607-27-9
    SMILES CC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F
    Synonyms WNK-463, WNK 463
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 81 mg/mL (174.77 mM)
    Water Insoluble
    Ethanol 81 mg/mL (174.77 mM)
    In vivo 5% DMSO+30%PEG 300+5% Tween 80+ddH2O 7 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.58 mL 107.88 mL 215.77 mL
    0.5 mM 4.32 mL 21.58 mL 43.15 mL
    1 mM 2.16 mL 10.79 mL 21.58 mL
    5 mM 0.43 mL 2.16 mL 4.32 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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