NVP-BGT226

Catalog No.: A11162
PI3K inhibitor

NVP-BGT226, novel phosphoinositide 3-kinase/mTOR dual inhibitor, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.

Grouped product items
Product Name Price Stock Qty
NVP-BGT226 5mg
$120.00
In stock
NVP-BGT226 10mg
$205.00
In stock
NVP-BGT226 50mg
$650.00
In stock
NVP-BGT226 200mg
$1,800.00
In stock
NVP-BGT226 10mM * 1mL in DMSO
$200.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription

NVP-BGT226, novel phosphoinositide 3-kinase/mTOR dual inhibitor, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo.

Targets
Target Value
Product Information
Catalog Num A11162
Formula C28H25F3N6O2.C4H4O4
Molecular Weight 650.6
CAS Number 1245537-68-1
SMILES CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC.C(=C\C(=O)O)\C(=O)O
Synonyms NVPBGT226, BGT226, BGT-226
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 27 mg/mL (41.5 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.37 mL 76.85 mL 153.7 mL
0.5 mM 3.07 mL 15.37 mL 30.74 mL
1 mM 1.54 mL 7.69 mL 15.37 mL
5 mM 0.31 mL 1.54 mL 3.07 mL
Useful Calculator

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