BMS303141

Catalog No.: A13807
ATP-citrate lyase inhibitor
BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Grouped product items
Product Name Price Stock Qty
BMS303141 10mg
$85.00
In stock
BMS303141 25mg
$160.00
In stock
BMS303141 50mg
$300.00
In stock
BMS303141 100mg
$480.00
In stock
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Biological Activity
Discription BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Product Information
Catalog Num A13807
Formula C19H15Cl2NO4S
Molecular Weight 424.3
CAS Number 943962-47-8
SMILES COC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl
Synonyms BMS 303141, BMS-303141
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 73 mg/mL (172.04 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.57 mL 117.84 mL 235.68 mL
0.5 mM 4.71 mL 23.57 mL 47.14 mL
1 mM 2.36 mL 11.78 mL 23.57 mL
5 mM 0.47 mL 2.36 mL 4.71 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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