CZC54252 hydrochloride

Catalog No.: A15510
LRRK2 inhibitor
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
Grouped product items
Product Name Price Stock Qty
CZC54252 hydrochloride 10mg
$120.00
In stock
CZC54252 hydrochloride 25mg
$250.00
In stock
CZC54252 hydrochloride 50mg
$420.00
In stock
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Biological Activity
Discription CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
Product Information
Catalog Num A15510
Formula C22H25ClN6O4S.HCl
Molecular Weight 541.45
CAS Number 1191911-27-9
SMILES COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl
Synonyms CZC-54252 hydrochloride, CZC 54252 hydrochloride
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 85 mg/mL (168.32 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.47 mL 92.34 mL 184.69 mL
0.5 mM 3.69 mL 18.47 mL 36.94 mL
1 mM 1.85 mL 9.23 mL 18.47 mL
5 mM 0.37 mL 1.85 mL 3.69 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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