Cisplatin

Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
Grouped product items
Product Name Price Stock Qty
Cisplatin 250mg
$60.00
In stock
Cisplatin 2g
$400.00
In stock
Cisplatin 10mM * 1mL in DMSO
$60.00
In stock
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Important Notice: For research use only. We do not sell to patients.

Prop65 Warning  WARNING: Attention California Residents: This product can expose you to chemicals including Cisplatin , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Adooq Products cited in reputable paper
Adooq's Cisplatin has been cited by 10 publications
  • Jintian Song, .et al. , J Cancer, 2023, May 21;14(9):1515-1530 PMID: 37325046
  • Huan Li, Srinivas Chatla, .et al. , Res Sq, 2023, Apr 6;rs.3.rs-2688694 PMID: 37066268
  • Min-Yung Kuo, .et al. , Int J Mol Sci, 2022, Dec 21;24(1):138 PMID: 36613579
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • RUI-NING LIANG, .et al. , Research Square, 2022, July 6th
  • Wei Zeng, .et al. , Exp Ther Med, 2021, May; 21(5): 424 PMID: 33747163
  • Yi-Ru Pan, .et al. , Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
  • Amnah Alshangiti, .et al. , Neuronal Signal, 2019, 2019
  • Calhelha RC, .et al. , Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301
  • Pi-Lin Sung, .et al. , Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408
  • Biological Activity
    Discription Cisplatin was the first member of a class of platinum-containing anti-cancer drugs, which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA, which ultimately triggers apoptosis (programmed cell death).
    Targets
    Target Value
    Product Information
    Catalog Num A10221
    Formula Cl2H4N2Pt
    Molecular Weight 300.1
    CAS Number 15663-27-1
    SMILES N.N.Cl[Pt+2]Cl
    Synonyms cisplatinum, CDDP, cis-diamminedichloroplatinum(II)
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 56 mg/mL (186.63 mM)
    Water DMF: 11 mg/mL (36.66 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 33.32 mL 166.61 mL 333.22 mL
    0.5 mM 6.66 mL 33.32 mL 66.64 mL
    1 mM 3.33 mL 16.66 mL 33.32 mL
    5 mM 0.67 mL 3.33 mL 6.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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