HMN-214

Catalog No.: A10452
PLK Inhibitor
HMN-214 inhibits polo-like and cyclin-dependent kinase activity, has potent antimicrotubular effects and results in profound apoptosis and antitumor activity in a broad spectrum of human xenografts.
Grouped product items
Product Name Price Stock Qty
HMN-214 5mg
$90.00
In stock
HMN-214 10mg
$160.00
In stock
HMN-214 50mg
$580.00
In stock
HMN-214 100mg
$920.00
In stock
HMN-214 10mM * 1mL in DMSO
$135.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription HMN-214 inhibits polo-like and cyclin-dependent kinase activity, has potent antimicrotubular effects and results in profound apoptosis and antitumor activity in a broad spectrum of human xenografts.
Targets
Target Value
Product Information
Catalog Num A10452
Formula C22H20N2O5S
Molecular Weight 424.5
CAS Number 173529-46-9
SMILES CC(=O)N(C1=CC=CC=C1/C=C/C2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC
Synonyms IVX-214
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 11 mg/mL (25.91 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.56 mL 117.79 mL 235.57 mL
0.5 mM 4.71 mL 23.56 mL 47.11 mL
1 mM 2.36 mL 11.78 mL 23.56 mL
5 mM 0.47 mL 2.36 mL 4.71 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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