Irinotecan HCl Trihydrate (Campto)

Catalog No.: A10479
Topoisomerase inhibitor
Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.
Grouped product items
Product Name Price Stock Qty
Irinotecan HCl Trihydrate 200mg
$110.00
In stock
Irinotecan HCl Trihydrate 10mM * 1mL in DMSO
$61.00
In stock
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Biological Activity
Discription Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.
Targets
Target Value
Product Information
Catalog Num A10479
Formula C33H38N4O6.HCl.3H2O
Molecular Weight 677.2
CAS Number 136572-09-3
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl
Synonyms CPT 11, Camptosar
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (135.86 mM)
Water 1 mg/mL (1.47 mM)
Ethanol 6 mg/mL (8.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.77 mL 73.83 mL 147.67 mL
0.5 mM 2.95 mL 14.77 mL 29.53 mL
1 mM 1.48 mL 7.38 mL 14.77 mL
5 mM 0.3 mL 1.48 mL 2.95 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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