PF 573228

Catalog No.: A11235
FAK Inhibitor
PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).
Grouped product items
Product Name Price Stock Qty
PF 573228 10mg
$80.00
In stock
PF 573228 25mg
$150.00
In stock
PF 573228 50mg
$250.00
In stock
PF 573228 100mg
$400.00
In stock
PF 573228 10mM * 1mL in DMSO
$98.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PF 573228 has been cited by 2 publications
  • Izumi D, .et al. , Int J Cancer, 2016, Mar 1;138(5):1207-19 PMID: 26414794
  • Aya Yokota-Nakatsuma, .et al. , Sci Rep, 2016, 6: 37914 PMID: 27897208
  • Biological Activity
    Discription PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A11235
    Formula C22H20F3N5O3S
    Molecular Weight 491.5
    CAS Number 869288-64-2
    SMILES CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
    Synonyms PF-573228, PF573228
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 24 mg/mL (48.83 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+2% Tween 80+30% PEG 300+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.35 mL 101.73 mL 203.46 mL
    0.5 mM 4.07 mL 20.35 mL 40.69 mL
    1 mM 2.03 mL 10.17 mL 20.35 mL
    5 mM 0.41 mL 2.03 mL 4.07 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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