SEA0400

Catalog No.: A15236
NCX inhibitor
SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).
Grouped product items
Product Name Price Stock Qty
SEA0400 5mg
$76.00
In stock
SEA0400 10mg
$129.00
In stock
SEA0400 50mg
$380.00
In stock
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Adooq Products cited in reputable paper
Adooq's SEA0400 has been cited by 1 publications
  • Wakana Shoda, .et al. , PLoS One, 2020, 15(6): e0235360 PMID: 32603346
  • Biological Activity
    Discription SEA0400 is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia).
    Product Information
    Catalog Num A15236
    Formula C21H19F2NO3
    Molecular Weight 371.38
    CAS Number 223104-29-8
    SMILES CCOC1=CC(=C(C=C1)OC2=CC=C(C=C2)OCC3=C(C=CC(=C3)F)F)N
    Synonyms SEA 0400, SEA-0400
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 63 mg/mL (169.63 mM)
    Water Insoluble
    Ethanol 63 mg/mL (169.63 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.93 mL 134.63 mL 269.27 mL
    0.5 mM 5.39 mL 26.93 mL 53.85 mL
    1 mM 2.69 mL 13.46 mL 26.93 mL
    5 mM 0.54 mL 2.69 mL 5.39 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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