12-O-tetradecanoyl phorbol-13-acetate

12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
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Product Name Price Stock Qty
12-O-tetradecanoyl phorbol-13-acetate 5mg
$105.00
In stock
12-O-tetradecanoyl phorbol-13-acetate 10mg
$150.00
In stock
12-O-tetradecanoyl phorbol-13-acetate 25mg
$270.00
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Biological Activity
Discription 12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
Targets
Target Value
Product Information
Catalog Num A14616
Formula C36H56O8
Molecular Weight 616.83
CAS Number 16561-29-8
SMILES CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
Synonyms TPA, Phorbol 12-myristate 13-acetate
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 94 mg/mL (152.38 mM)
Water Insoluble
Ethanol 94 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.21 mL 81.06 mL 162.12 mL
0.5 mM 3.24 mL 16.21 mL 32.42 mL
1 mM 1.62 mL 8.11 mL 16.21 mL
5 mM 0.32 mL 1.62 mL 3.24 mL
Useful Calculator

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