PRX-08066

Catalog No.: A13267
5-HT2B receptor antagonist
PRX-08066, a Novel 5-Hydroxytryptamine Receptor 2B Antagonist, reduced monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats.
Grouped product items
Product Name Price Stock Qty
PRX-08066 5mg
$190.00
In stock
PRX-08066 10mg
$280.00
In stock
PRX-08066 25mg
$570.00
In stock
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Biological Activity
Discription PRX-08066, a Novel 5-Hydroxytryptamine Receptor 2B Antagonist, reduced monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats.
Targets
Target Value
Product Information
Catalog Num A13267
Formula C19H17ClFN5S
Molecular Weight 401.89
CAS Number 866206-54-4
SMILES C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N
Synonyms PRX08066, PRX 08066
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (177.61 mM)
Water 92 mg/mL (177.61 mM)
Ethanol 86 mg/mL (166.03 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.88 mL 124.41 mL 248.82 mL
0.5 mM 4.98 mL 24.88 mL 49.76 mL
1 mM 2.49 mL 12.44 mL 24.88 mL
5 mM 0.5 mL 2.49 mL 4.98 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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