(S)-crizotinib

Catalog No.: A14291
MTH1 (NUDT1) inhibitor
(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.
Grouped product items
Product Name Price Stock Qty
(S)-crizotinib 10mg
$150.00
In stock
(S)-crizotinib 25mg
$300.00
In stock
(S)-crizotinib 50mg
$500.00
In stock
(S)-crizotinib 10mM * 1mL in DMSO
$127.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription (S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.
Targets
Target Value
Product Information
Catalog Num A14291
Formula C21H22Cl2FN5O
Molecular Weight 450.34
CAS Number 1374356-45-2
SMILES C[C@@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 42 mg/mL (93.26 mM)
Water Insoluble
Ethanol 22 mg/mL (48.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.21 mL 111.03 mL 222.05 mL
0.5 mM 4.44 mL 22.21 mL 44.41 mL
1 mM 2.22 mL 11.1 mL 22.21 mL
5 mM 0.44 mL 2.22 mL 4.44 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy (S)-crizotinib | (S)-crizotinib Supplier | purchase (S)-crizotinib | (S)-crizotinib cost | (S)-crizotinib manufacturer | order (S)-crizotinib | (S)-crizotinib distributor | buy 1374356-45-2 | 1374356-45-2 Supplier | purchase 1374356-45-2 | 1374356-45-2 cost | 1374356-45-2 manufacturer | order 1374356-45-2 | 1374356-45-2 distributor