DMXAA (ASA404, Vadimezan)

Catalog No.: A10324

Vascular Disrupting Agent (VDA)

DMXAA (ASA404, Vadimezan)

DMXAA (ASA404, Vadimezan) Chemical Structure

CAS NO. 117570-53-3

DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $260.00

Special Price $234.00

50 mg

Regular Price: $450.00

Special Price $405.00

100 mg

Regular Price: $700.00

Special Price $630.00

10mM * 1mL in DMSO

Regular Price: $104.00

Special Price $93.60

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
Targets
DT-diaphorase (Cell-free assay) DT-diaphorase (Cell-free assay)
20 μM(Ki)20 μM(Ki)
In vitro (25°C) DMSO 7 mg/mL (24.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.42 mL 177.12 mL 354.23 mL
0.5 mM 7.08 mL 35.42 mL 70.85 mL
1 mM 3.54 mL 17.71 mL 35.42 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10324
Actions No
M. Wt 282.3
Formula C17H14O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 117570-53-3
Synonyms AS-1404, 5,6-MeXAA, NSC-640488, Vadimezan
SMILES CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C

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