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Edoxaban (tosylate Monohydrate)

Catalog No.: A14317

Factor Xa inhibitor

Edoxaban (tosylate Monohydrate)

Edoxaban (tosylate Monohydrate) Chemical Structure

CAS NO. 1229194-11-9

Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM

Availability: In stock

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10 mg
25 mg
50 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Daniël Verhoef, .et al. Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors, Nat Commun, 2017, 8: 528 PMID: 28904343

Biological Activity

Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM
Factor Xa Thrombin FIXa
0.561 nM(Ki)6 μM(Ki)41.7 μM(Ki)
In vitro DMSO 89 mg/mL (120.55 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.55 mL 67.73 mL 135.45 mL
0.5 mM 2.71 mL 13.55 mL 27.09 mL
1 mM 1.35 mL 6.77 mL 13.55 mL
5 mM 0.27 mL 1.35 mL 2.71 mL

*The above data is based on the productmolecular weight 738.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14317
Actions Inhibitor
CAS No. 1229194-11-9
Formula C24H30ClN7O4S.C7H8O3S.H2O
M. Wt 738.27
Purity >98%
Synonyms DU-176b
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCC2=C(C1)SC(=N2)C(=O)N[[email protected]@H]3C[[email protected]](CC[[email protected]@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C.O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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