Elvitegravir (GS-9137)

Catalog No.: A10347

HIV integrase inhibitor

Elvitegravir (GS-9137)

Elvitegravir (GS-9137) Chemical Structure

CAS NO. 697761-98-1

Elvitegravir (GS-9137) is a potent inhibitor of the strand-transfer step of integration mediated by human immunodeficiency virus type 1 (HIV-1) integrase.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $60.00

Special Price $54.00

50 mg

Regular Price: $280.00

Special Price $252.00

100 mg

Regular Price: $520.00

Special Price $468.00

10mM * 1mL in DMSO

Regular Price: $86.00

Special Price $77.40

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Elvitegravir (GS-9137) is a potent inhibitor of the strand-transfer step of integration mediated by human immunodeficiency virus type 1 (HIV-1) integrase.
Targets
HIV-1 IIIB (Cell-free assay) HIV-2 ROD (Cell-free assay) HIV-2 EHO (Cell-free assay)
0.7 nM1.4 nM2.8 nM
In vitro DMSO 90 mg/mL (200.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 35 mg/mL (78.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.33 mL 111.63 mL 223.26 mL
0.5 mM 4.47 mL 22.33 mL 44.65 mL
1 mM 2.23 mL 11.16 mL 22.33 mL
5 mM 0.45 mL 2.23 mL 4.47 mL

*The above data is based on the productmolecular weight 447.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10347
Actions Inhibitor
M. Wt 447.9
Formula C23H23ClFNO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 697761-98-1
Synonyms GS9137
SMILES CC(C)[[email protected]@H](CO)N1C=C(C(=O)C2=CC(=C(C=C21)OC)CC3=C(C(=CC=C3)Cl)F)C(=O)O

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