Catalog No.: A12043

COX-1 inhibitor


(-)-Epicatechin Chemical Structure

CAS NO. 490-46-0

(-)-Epicatechin is a natural product from green tea. (-)Epicatechin is an inhibitor of Cox-1

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • A S D'Costa, .et al. Inhibition of starch digestion by flavonoids: Role of flavonoid-amylase binding kinetics, Food Chem, 2020, Oct 1;341(Pt 2):128256 PMID: 33035827
  • Mihaela Tudorache, .et al. Phenolic compounds mediate aggregation of water-soluble polysaccharides and change their rheological properties: Effect of different phenolic compounds, Food Hydrocoll, 2019, 97, Dec, 105193
  • Md Shajedul Islam, .et al. UV-C irradiation as an alternative disinfection technique: Study of its effect on polyphenols and antioxidant activity of apple juice, Innovative food science & emerging technologies, 2016, v.34 pp. 344-351
  • Islam MS, .et al. Effect of UV Irradiation on the Nutritional Quality and Cytotoxicity of Apple Juice, J Agric Food Chem, 2016, Oct 10 PMID: 27632812

Biological Activity

(-)-Epicatechin is a natural product from green tea. (-)Epicatechin is an inhibitor of Cox-1
In vitro DMSO 52 mg/mL (179.14 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.45 mL 172.25 mL 344.51 mL
0.5 mM 6.89 mL 34.45 mL 68.9 mL
1 mM 3.45 mL 17.23 mL 34.45 mL
5 mM 0.69 mL 3.45 mL 6.89 mL

*The above data is based on the productmolecular weight 290.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12043
Actions Inhibitor
CAS No. 490-46-0
Formula C15H14O6
M. Wt 290.27
Purity >98%
Synonyms (?)Epicatechin
SMILES C1[[email protected]]([[email protected]](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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