Epothilone A

Catalog No.: A10359

Microtubule Associated inhibitor

Epothilone A

Epothilone A Chemical Structure

CAS NO. 152044-53-6

Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$180.00
25 mg
$350.00
10mM * 1mL in DMSO
$160.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity.
Targets
Tubulin
2 μM(EC0.01)
In vitro DMSO 99 mg/mL (200.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol 99 mg/mL (200.54 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.28 mL 202.55 mL
0.5 mM 4.05 mL 20.26 mL 40.51 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10359
Actions Inhibitor
M. Wt 493.7
Formula C26H39NO6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 152044-53-6
Synonyms EpoA, Epothilone-A
SMILES C[[email protected]]1CCC[[email protected]@H]2[[email protected]@H](O2)C[[email protected]](OC(=O)C[[email protected]@H](C(C(=O)[[email protected]@H]([[email protected]]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C

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