Catalog No.: A13328

ATR inhibitor


ETP-46464 Chemical Structure

CAS NO. 1345675-02-6

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.

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Biological Activity

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
0.6 nM14 nM36 nM170 nM545 nM
In vitro DMSO 6 mg/mL (12.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.53 mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL

*The above data is based on the productmolecular weight 470.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13328
Actions Inhibitor
M. Wt 470.52
Formula C30H22N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1345675-02-6
Synonyms ETP46464, ETP 46464

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