ETP-46464

Name: ETP-46464
SKU: A13328
Price: 140 USD
Rating: 5 (1 reviews)

Catalog No.: A13328

ATR inhibitor

Adooq's ETP-46464 has been cited by 1 publications

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.

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Data Sheet

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Adooq Products cited in reputable paper

Adooq's ETP-46464 has been cited by 1 publications

Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458

Biological Activity

Discription

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.

Targets

Target	Value

Chemical Information

Catalog Num	A13328
Formula	C30H22N4O2
Molecular Weight	470.52
CAS Number	1345675-02-6
SMILES	CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5
Synonyms	ETP46464, ETP 46464
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	6 mg/mL (12.75 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.25 mL	106.27 mL	212.53 mL
0.5 mM	4.25 mL	21.25 mL	42.51 mL
1 mM	2.13 mL	10.63 mL	21.25 mL
5 mM	0.43 mL	2.13 mL	4.25 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Product Name	Price	Stock
ETP-46464 10mg	$140.00	In stock
ETP-46464 25mg	$280.00	In stock
ETP-46464 50mg	$500.00	In stock

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