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$0.00 - Steve U. Ayobahan, .et al. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure, Sci Rep, 2019, 9, Article number: 6599
- Muth-Köhne E, .et al. Linking the response of endocrine regulated genes to adverse effects on sex differentiation improves comprehension of aromatase inhibition in a Fish Sexual Development Test, Aquat Toxicol, 2016, Jul;176:116-27 PMID: 27130971
- Ma YN, .et al. Effects of azocyclotin on gene transcription and steroid metabolome of hypothalamic-pituitary-gonad axis, and their consequences on reproduction in zebrafish (Danio rerio), Aquat Toxicol, 2016, Oct;179:55-64 PMID: 27571716
Biological Activity
Fadrozole is a nonsteroidal aromatase inhibitor exhibiting a very potent and selective inhibitory effect of the aromatase enzyme system in vivo and estrogen biosynthesis in vivo.
| In vitro | DMSO | 42 mg/mL (188.1 mM) | |
| Water | Insoluble | ||
| Ethanol | 42 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.79 mL | 223.94 mL | 447.89 mL |
| 0.5 mM | 8.96 mL | 44.79 mL | 89.58 mL |
| 1 mM | 4.48 mL | 22.39 mL | 44.79 mL |
| 5 mM | 0.9 mL | 4.48 mL | 8.96 mL |
*The above data is based on the productmolecular weight 223.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11088 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 102676-47-1 |
| Formula | C14H13N3 |
| M. Wt | 223.27 |
| Purity | >98% |
| SMILES | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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