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$0.00 - Steve U. Ayobahan, .et al. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure, Sci Rep, 2019, 9, Article number: 6599
- Muth-Köhne E, .et al. Linking the response of endocrine regulated genes to adverse effects on sex differentiation improves comprehension of aromatase inhibition in a Fish Sexual Development Test, Aquat Toxicol, 2016, Jul;176:116-27 PMID: 27130971
- Ma YN, .et al. Effects of azocyclotin on gene transcription and steroid metabolome of hypothalamic-pituitary-gonad axis, and their consequences on reproduction in zebrafish (Danio rerio), Aquat Toxicol, 2016, Oct;179:55-64 PMID: 27571716
Biological Activity
Fadrozole is a nonsteroidal aromatase inhibitor exhibiting a very potent and selective inhibitory effect of the aromatase enzyme system in vivo and estrogen biosynthesis in vivo.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.79 mL | 223.94 mL | 447.89 mL |
| 0.5 mM | 8.96 mL | 44.79 mL | 89.58 mL |
| 1 mM | 4.48 mL | 22.39 mL | 44.79 mL |
| 5 mM | 0.9 mL | 4.48 mL | 8.96 mL |
*The above data is based on the productmolecular weight 223.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11088 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 223.27 |
| Formula | C14H13N3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 102676-47-1 |
| SMILES | C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N |
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