Total item
Cart Subtotal
$0.00 - Huang-Ming Chang, .et al. FGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling, Cell Death Dis, 2021, Apr 17;12(5):409 PMID: 33866326
Biological Activity
FMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.21 mL | 146.04 mL | 292.08 mL |
| 0.5 mM | 5.84 mL | 29.21 mL | 58.42 mL |
| 1 mM | 2.92 mL | 14.6 mL | 29.21 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
*The above data is based on the productmolecular weight 342.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11423 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 821794-92-7 |
| Formula | C18H19FN4O2 |
| M. Wt | 342.37 |
| Purity | >98% |
| SMILES | CC1=CC=C(C=C1)C2=C(N(C3=C2C(=NC=N3)N)CCCO)C(=O)CF |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy FMK | FMK Supplier | purchase | cost | manufacturer | order | distributor | buy 821794-92-7| 821794-92-7 Supplier | purchase 821794-92-7 | 821794-92-7 cost | 821794-92-7 manufacturer | order 821794-92-7 | 821794-92-7 distributor
Adooq Quality Guarantee
We promise all products perform as described.