FRAX486

Catalog No.: A13691

PAK inhibitor

FRAX486

FRAX486 Chemical Structure

CAS NO. 1232030-35-1

FRAX486 is a small-molecule PAK inhibitor.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
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Biological Activity

FRAX486 is a small-molecule PAK inhibitor.
Targets
PAK1 PAK2 PAK3 PAK4
14 nM33 nM39 nM575 nM
In vitro DMSO 21 mg/mL (40.9 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.48 mL 97.39 mL 194.78 mL
0.5 mM 3.9 mL 19.48 mL 38.96 mL
1 mM 1.95 mL 9.74 mL 19.48 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 513.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13691
Actions Inhibitor
CAS No. 1232030-35-1
Formula C25H23Cl2FN6O
M. Wt 513.39
Purity >98%
Synonyms FRAX 486, FRAX-486
SMILES CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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