Fumagillin

Catalog No.: A15299

Aminopeptidase inhibitor

Fumagillin

Fumagillin Chemical Structure

CAS NO. 23110-15-8

Fumagillin is a complex natural product antibiotic which covalently binds a key histidine residue of methionine aminopeptidase type II (MetAP-2), inhibiting endothelial cell proliferation and angiogenesis.

Availability: In stock

Package Price Qty
1 mg
$65.00
5 mg
$210.00
10 mg
$480.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fumagillin is a complex natural product antibiotic which covalently binds a key histidine residue of methionine aminopeptidase type II (MetAP-2), inhibiting endothelial cell proliferation and angiogenesis.
Targets
MetAP2
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.81 mL 109.04 mL 218.08 mL
0.5 mM 4.36 mL 21.81 mL 43.62 mL
1 mM 2.18 mL 10.9 mL 21.81 mL
5 mM 0.44 mL 2.18 mL 4.36 mL

*The above data is based on the productmolecular weight 458.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15299
Actions Inhibitor
M. Wt 458.55
Formula C26H34O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 23110-15-8
Synonyms N/A
SMILES CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C

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