GLYX-13 (Rapastinel)

Catalog No.: A13576

NMDAR modulator

GLYX-13 (Rapastinel)

GLYX-13 (Rapastinel) Chemical Structure

CAS NO. 117928-94-6

GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor which is under development by Naurex as adjunctive therapy for treatment-resistant depression.

Availability: In stock

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2 mg

Regular Price: $110.00

Special Price $88.00

5 mg

Regular Price: $190.00

Special Price $152.00

10 mg

Regular Price: $315.00

Special Price $252.00

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Biological Activity

GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor which is under development by Naurex as adjunctive therapy for treatment-resistant depression.
In vitro DMSO 79 mg/mL (191.07 mM)
Water 79 mg/mL (191.07 mM)
Ethanol 79 mg/mL (191.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.93 mL 241.86 mL
0.5 mM 4.84 mL 24.19 mL 48.37 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13576
Actions Modulator
CAS No. 117928-94-6
Formula C18H31N5O6
M. Wt 413.47
Purity >98%
Synonyms GLYX 13, GLYX13
SMILES C[[email protected]]([[email protected]@H](C(=O)N1CCC[[email protected]]1C(=O)N2CCC[[email protected]]2C(=O)N[[email protected]@H]([[email protected]@H](C)O)C(=O)N)N)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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