GSK-650394

Catalog No.: A13309

SGK1 inhibitor

GSK-650394

GSK-650394 Chemical Structure

CAS NO. 890842-28-1

GSK 650394 is a glucocorticoid- and serum-regulated kinase 1 (SGK1) inhibitor which displays antiproliferative properties against the LNCaP prostate carcinoma cell line.

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$400.00
10mM * 1mL in DMSO
$105.00
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Biological Activity

GSK 650394 is a glucocorticoid- and serum-regulated kinase 1 (SGK1) inhibitor which displays antiproliferative properties against the LNCaP prostate carcinoma cell line.
Targets
SGK1 SGK2
62 nM103 nM
In vitro DMSO 76 mg/mL (198.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.74 mL 261.47 mL
0.5 mM 5.23 mL 26.15 mL 52.29 mL
1 mM 2.61 mL 13.07 mL 26.15 mL
5 mM 0.52 mL 2.61 mL 5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13309
Actions Inhibitor
M. Wt 382.45
Formula C25H22N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 890842-28-1
Synonyms GSK 650394, GSK650394
SMILES C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O

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