Catalog No.: A10438
mTOR/PI3K Inhibitor
GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM).
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GSK1059615 5mg
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Adooq Products cited in reputable paper
Adooq's GSK1059615 has been cited by 1 publications
  • Jing Xie, .et al. , Oncotarget, 2017, Aug 1; 8(31): 50814-50823 PMID: 28881606
  • Biological Activity
    Discription GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM).
    Target Value
    Product Information
    Catalog Num A10438
    Formula C18H11N3O2S
    Molecular Weight 333.4
    CAS Number 958852-01-2
    SMILES C1=CC2=NC=CC(=C2C=C1/C=C\3/C(=O)NC(=O)S3)C4=CC=NC=C4

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO 2 mg/mL (5.99 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 29.99 mL 149.97 mL 299.94 mL
    0.5 mM 6 mL 29.99 mL 59.99 mL
    1 mM 3 mL 15 mL 29.99 mL
    5 mM 0.6 mL 3 mL 6 mL
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    Calculate the dilution required to prepare a stock solution.
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