GSK1059615

Catalog No.: A10438

mTOR/PI3K Inhibitor

GSK1059615 Chemical Structure

CAS NO. 958852-01-2

GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM).

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
25 mg
$250.00
50 mg
$450.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM).
Targets
PI3Kα PI3Kβ PI3Kδ PI3Kγ mTOR
0.4 nM0.6 nM2 nM5 nM12 nM
In vitro DMSO 2 mg/mL (5.99 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.99 mL 149.97 mL 299.94 mL
0.5 mM 6 mL 29.99 mL 59.99 mL
1 mM 3 mL 15 mL 29.99 mL
5 mM 0.6 mL 3 mL 6 mL

*The above data is based on the productmolecular weight 333.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10438
Actions Inhibitor
M. Wt 333.4
Formula C18H11N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 958852-01-2
Synonyms GSK-1059615
SMILES C1=CC2=NC=CC(=C2C=C1/C=C\3/C(=O)NC(=O)S3)C4=CC=NC=C4

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