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Guanylate cyclase C agonist
Linaclotide is a peptide agonist of the guanylate cyclase 2C. -
GC-C receptor agonist
Plecanatide acetate is a guanylate cyclase-C (GC-C) receptor agonist, with an EC50 of 190 nM in T84 cells. Plecanatide acetate shows anti-inflammatory activity in models of murine colitis.
