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H-1152 dihydrochloride, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.49 mL | 127.44 mL | 254.88 mL |
| 0.5 mM | 5.1 mL | 25.49 mL | 50.98 mL |
| 1 mM | 2.55 mL | 12.74 mL | 25.49 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 392.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15102 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 871543-07-6 |
| Formula | C16H23Cl2N3O2S |
| M. Wt | 392.34 |
| Purity | >98% |
| Synonyms | H 1152 dihydrochloride, H1152 dihydrochloride |
| SMILES | CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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