H-1152 dihydrochloride

Catalog No.: A15102

ROCK inhibitor

H-1152 dihydrochloride

H-1152 dihydrochloride Chemical Structure

CAS NO. 871543-07-6

H-1152 dihydrochloride, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $135.00

Special Price $108.00

10 mg

Regular Price: $252.00

Special Price $201.60

50 mg

Regular Price: $550.00

Special Price $440.00

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Biological Activity

H-1152 dihydrochloride, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.49 mL 127.44 mL 254.88 mL
0.5 mM 5.1 mL 25.49 mL 50.98 mL
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15102
Actions Inhibitor
CAS No. 871543-07-6
Formula C16H23Cl2N3O2S
M. Wt 392.34
Purity >98%
Synonyms H 1152 dihydrochloride, H1152 dihydrochloride
SMILES CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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