β-catenin

13 Item(s)

per page

Set Descending Direction
  1. ICG-001

    Catalog No. A11039
    Quick View
    Wnt/beta-catenin inhibitor
    ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) . Learn More
  2. iCRT3

    Catalog No. A16847
    Quick View
    Wnt/β-catenin antagonist
    iCRT3 is an antagonist of Wnt/β-catenin signaling with an IC50 of 8.2 nM in the Wnt responsive STF16-luc reporter assays. Learn More
  3. KYA1797K

    Catalog No. A16353
    Quick View
    Wnt/beta-catenin inhibitor
    KYA1797K is a highly potent and selective Wnt/beta-catenin inhibitor with IC50 of 0.75 μM (TOPflash assay). Learn More
  4. iCRT 14

    Catalog No. A16218
    Quick View
    CRT inhibitor
    iCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Learn More
  5. Hexachlorophene

    Catalog No. A16217
    Quick View
    Wnt/beta-catenin inhibitor
    Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 uM; also is an inhibitor of Wnt/beta-catenin signaling. Learn More
  6. Cardiogenol C HCl

    Catalog No. A16198
    Quick View
    Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 uM. Cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Learn More
  7. IQ-1

    Catalog No. A16064
    Quick View
    Wnt/beta-catenin inhibitor
    IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/beta-catenin signaling. Learn More
  8. PRI-724

    Catalog No. A15856
    Quick View
    CBP/beta-catenin antagonist

    PRI-724, an isomer or enantiomer of ICG-001 (A11039), is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity.

    Learn More
  9. Cardiogenol C hydrochloride

    Catalog No. A15773
    Quick View
    Cardiogenol C hydrochloride is a potent and cell permeable inducer of embryonic stem cell differentiation in cardiomyocytes displaying an Ec50 of 100nm. Learn More
  10. WAY-316606

    Catalog No. A13986
    sFRP-1 inhibitor
    WAY-316606 is a small molecule inhibitors of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Learn More
  11. FH535

    Catalog No. A13795
    Quick View
  12. IWR-1-endo

    Catalog No. A12737
    Quick View
    Wnt inhibitor
    IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. Learn More
  13. IWP-4

    Catalog No. A17004
    Quick View
    Wnt/β-catenin signaling inhibitor
    IWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling. Learn More

13 Item(s)

per page

Set Descending Direction
Rewards