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Hexachlorophene
Catalog No. A16217 Wnt/beta-catenin inhibitorHexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 uM; also is an inhibitor of Wnt/beta-catenin signaling. Learn More -
Longdaysin
Catalog No. A21022 Wnt/β-catenin signaling inhibitorLongdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling. Learn More -
SKL2001
Catalog No. A16707 Wnt/β-catenin agonistSKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction. Learn More -
HLY78
Catalog No. A18402 Wnt/β-catenin activatorHLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction. Learn More -
Wnt/β-catenin agonist 1
Catalog No. A18689 Wnt/β-catenin agonistWnt/β-catenin agonist 1 is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM. Learn More -
IWP-4
Catalog No. A17004 Wnt/β-catenin signaling inhibitorIWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling. Learn More -
iCRT3
Catalog No. A16847 Wnt/β-catenin antagonistiCRT3 is an antagonist of Wnt/β-catenin signaling with an IC50 of 8.2 nM in the Wnt responsive STF16-luc reporter assays. Learn More -
KYA1797K
Catalog No. A16353 Wnt/beta-catenin inhibitorKYA1797K is a highly potent and selective Wnt/beta-catenin inhibitor with IC50 of 0.75 μM (TOPflash assay). Learn More -
iCRT 14
Catalog No. A16218 CRT inhibitoriCRT 14 is a novel potent inhibitor of beta-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Learn More -
ICG-001
Catalog No. A11039 Wnt/beta-catenin inhibitorICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) . Learn More -
Cardiogenol C HCl
Catalog No. A16198 Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC- (myosin heavy chain) positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 uM. Cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Learn More -
IQ-1
Catalog No. A16064 Wnt/beta-catenin inhibitorIQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/beta-catenin signaling. Learn More -
Cardiogenol C hydrochloride
Catalog No. A15773 Cardiogenol C hydrochloride is a potent and cell permeable inducer of embryonic stem cell differentiation in cardiomyocytes displaying an Ec50 of 100nm. Learn More -
BC2059
Catalog No. A14381 beta-catenin inhibitorBC2059 is an orally bioavailable and potent beta-catenin inhibitor. Learn More -
WAY-316606
Catalog No. A13986 sFRP-1 inhibitorWAY-316606 is a small molecule inhibitors of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Learn More -
FH535
Catalog No. A13795 β-Catenin/Tcf InhibitorFH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities. Learn More -
IWR-1-endo
Catalog No. A12737 Wnt inhibitorIWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. Learn More
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