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Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.12 mL | 160.62 mL | 321.23 mL |
| 0.5 mM | 6.42 mL | 32.12 mL | 64.25 mL |
| 1 mM | 3.21 mL | 16.06 mL | 32.12 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.42 mL |
*The above data is based on the productmolecular weight 311.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13560 |
|---|---|
| Actions | Activator |
| CAS No. | 36945-98-9 |
| Formula | C16H13N3O4 |
| M. Wt | 311.3 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | AG 3-5 |
| SMILES | C1C=C(NC(=O)N1C2=CC=CC=C2O)C3=CC(=CC=C3)[N+](=O)[O-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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