Icilin

Catalog No.: A13560

TRPM8 and TRPA1 activator

Icilin

Icilin Chemical Structure

CAS NO. 36945-98-9

Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)

Availability: In stock

Package Price Qty
10 mg
$60.00
25 mg
$100.00
50 mg
$220.00
100 mg
$380.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.12 mL 160.62 mL 321.23 mL
0.5 mM 6.42 mL 32.12 mL 64.25 mL
1 mM 3.21 mL 16.06 mL 32.12 mL
5 mM 0.64 mL 3.21 mL 6.42 mL

*The above data is based on the productmolecular weight 311.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13560
Actions Activator
CAS No. 36945-98-9
Formula C16H13N3O4
M. Wt 311.3
Purity >98%
Synonyms AG 3-5
SMILES C1C=C(NC(=O)N1C2=CC=CC=C2O)C3=CC(=CC=C3)[N+](=O)[O-]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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