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Publications citing Adooq Products
Chemical Information
| Catalog Num | A10471 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 262.3 |
| Formula | C16H10N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 479-41-4 |
| Synonyms | Couroupitine B, Indigo red |
| SMILES code | C1=CC=C2C(=C1)/C(=C\3/C(=O)C4=CC=CC=C4N3)/C(=O)N2 |
| Chemical Name | 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one |
Description |
Indirubin, the active constituent of a Chinese antileukaemia medicine, is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. | ||||||||||||||||||||||||||||||||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 53 mg/mL (202.08 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.12 mL | 190.62 mL | 381.24mL |
| 0.5 mM | 7.62 mL | 38.12 mL | 76.25 mL |
| 1 mM | 3.81 mL | 19.06 mL | 38.12 mL |
| 5 mM | 0.76 mL | 3.81 mL | 7.62 mL |
*The above data is based on the productmolecular weight 262.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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