France
You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A10471 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 262.3 |
| Formula | C16H10N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 479-41-4 |
| Synonyms | Couroupitine B, Indigo red |
| SMILES code | C1=CC=C2C(=C1)/C(=C\3/C(=O)C4=CC=CC=C4N3)/C(=O)N2 |
| Chemical Name | 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one |
Description |
Indirubin, the active constituent of a Chinese antileukaemia medicine, is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. | ||||||||||||||||||||||||||||||||||||||||
Targets |
|
||||||||||||||||||||||||||||||||||||||||
| Solubility (25°C)* | In vitro | DMSO | 53 mg/mL (202.08 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.12 mL | 190.62 mL | 381.24mL |
| 0.5 mM | 7.62 mL | 38.12 mL | 76.25 mL |
| 1 mM | 3.81 mL | 19.06 mL | 38.12 mL |
| 5 mM | 0.76 mL | 3.81 mL | 7.62 mL |
*The above data is based on the productmolecular weight 262.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
€42.75
PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. ...
Special Price Starting at: €42.75
Special Price Starting at:
€68.40
AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. ...
Special Price Starting at: €68.40
Special Price Starting at:
€190.00
NVP-LCQ195 is a small molecule heterocyclic inhibitor of CDK1, CDK2, CDK3 and CDK5 with IC50 of 1-42 nM. ...
Special Price Starting at: €190.00
Special Price Starting at:
€51.30
Flavopiridol HCl is an inhibitor of cyclin-dependent kinases. The (-)-cis form induces apoptosis in particular tumor cells. ...
Special Price Starting at: €51.30
Special Price Starting at:
€153.90
P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. In Phase 2/3 ...
Special Price Starting at: €153.90
Special Price Starting at:
€59.85
Dinaciclib (SCH 727965) is a potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively. ...
Special Price Starting at: €59.85
Special Price Starting at:
€361.00
CVT-313 is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1). ...
Special Price Starting at: €361.00
Special Price Starting at:
€59.85
AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. ...
Special Price Starting at: €59.85
Special Price Starting at:
€51.30
LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. ...
Special Price Starting at: €51.30
Special Price Starting at:
€59.85
PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
...
Special Price Starting at: €59.85
PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
...
Special Price Starting at:
€188.10
PHA-690509 is a ATP-competitive CDK inhibitor. ...
Special Price Starting at: €188.10
Special Price Starting at:
€95.00
NU2058 is a guanine-based CDK inhibitor with IC50 of 17 uM and 26 uM for CDK2 and CDK1. ...
Special Price Starting at: €95.00
Special Price Starting at:
€34.20
SNS-032 (BMS-387032) is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B c ...
Special Price Starting at: €34.20
Special Price Starting at:
€114.00
NU6102 is selective for CDK1 and CDK2 compared to CDK4/D1 (IC50=1.6 μM), DYRK1A (IC50=0.9 μM), PDK1 (IC50=0.8 μM) and ROCKII (IC50=0.6 μM).
...
Special Price Starting at: €114.00
Special Price Starting at:
€47.50
AZD5438 is a potent inhibitor of cyclin-dependent kinase (CDK) 1, 2 and 9 (IC50 values are 16, 6 and 20 nM respectively). ...
Special Price Starting at: €47.50
Special Price Starting at:
€76.00
LDC000067 is a highly selective CDK9 inhibitor . ...
Special Price Starting at: €76.00
Special Price Starting at:
€34.20
Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia. ...
Special Price Starting at: €34.20
Special Price Starting at:
€85.50
CGP60474 is a potent inhibitor of cyclin-dependent kinase (CDK). ...
Special Price Starting at: €85.50
Special Price Starting at:
€114.00
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CDK7. ...
Special Price Starting at: €114.00
Special Price Starting at:
€114.00
JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays. It also potently inhibits Auror ...
Special Price Starting at: €114.00
Special Price Starting at:
€68.40
LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. ...
Special Price Starting at: €68.40
Special Price Starting at:
€76.95
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with much less effect other kinases. ...
Special Price Starting at: €76.95
Special Price Starting at:
€85.50
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and c ...
Special Price Starting at: €85.50
Special Price Starting at:
€119.70
BS-181 HCl is a potential anti-tumor agent as CDK7 inhibitor. ...
Special Price Starting at: €119.70
Special Price Starting at:
€102.60
BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. ...
Special Price Starting at: €102.60
Special Price Starting at:
€59.85
R547 is a novel, selective inhibitor of cell cycle and transcriptional cyclin dependent kinases (CDKs) (Ki = 1, 3, and 1 nM for CDK1, CDK2, and CDK4, respectively) with ...
Special Price Starting at: €59.85
R547 is a novel, selective inhibitor of cell cycle and transcriptional cyclin dependent kinases (CDKs) (Ki = 1, 3, and 1 nM for CDK1, CDK2, and CDK4, respectively) with ...
Special Price Starting at:
€95.00
AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. ...
Special Price Starting at: €95.00
Special Price Starting at:
€256.50
LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and ...
Special Price Starting at: €256.50
Special Price Starting at:
€76.95
PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity against several cancer cell lines. ...
Special Price Starting at: €76.95
Special Price Starting at:
€332.50
BAY 1000394 is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. ...
Special Price Starting at: €332.50
Keywords:buy Indirubin | Indirubin Supplier | purchase Indirubin | Indirubin cost | Indirubin manufacturer | order Indirubin | Indirubin distributor | buy 479-41-4 | 479-41-4 Supplier | purchase 479-41-4 | 479-41-4 cost | 479-41-4 manufacturer | order 479-41-4 | 479-41-4 distributor
We Using Safe Payments:
