Indomethacin (Indocid, Indocin)

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
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Size Price Stock Qty
100mg
$25.00
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500mg
$40.00
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1g
$45.00
In stock
5g
$105.00
In stock
10mM * 1mL in DMSO
$45.00
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Important Notice: For research use only. We do not sell to patients.

Adooq Products cited in reputable paper
Adooq's Indomethacin (Indocid, Indocin) has been cited by 3 publications
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
  • Biological Activity
    Discription Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10474
    Formula C19H16ClNO4
    Molecular Weight 357.79
    CAS Number 53-86-1
    SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
    Synonyms Indomethacin, Indochron E-R, Indocin-SR, Indocid
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 63 mg/mL (176.08 mM)
    Water Insoluble
    Ethanol 21 mg/mL (58.69 mM)
    In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.95 mL 139.75 mL 279.49 mL
    0.5 mM 5.59 mL 27.95 mL 55.9 mL
    1 mM 2.79 mL 13.97 mL 27.95 mL
    5 mM 0.56 mL 2.79 mL 5.59 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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