Indomethacin (Indocid, Indocin)

Catalog No.: A10474

COX inhibitor

Indomethacin (Indocid, Indocin)

Indomethacin (Indocid, Indocin) Chemical Structure

CAS NO. 53-86-1

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.

Availability: In stock

Package Price Qty
100 mg

Regular Price: $50.00

Special Price $40.00

250 mg

Regular Price: $100.00

Special Price $80.00

500 mg

Regular Price: $180.00

Special Price $144.00

1000 mg

Regular Price: $330.00

Special Price $264.00

10mM * 1mL in DMSO
$61.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
Targets
COX1 COX-2
0.28 μM14 μM
In vitro DMSO 72 mg/mL (201.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol 24 mg/mL (67.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.95 mL 139.75 mL 279.49 mL
0.5 mM 5.59 mL 27.95 mL 55.9 mL
1 mM 2.79 mL 13.97 mL 27.95 mL
5 mM 0.56 mL 2.79 mL 5.59 mL

*The above data is based on the productmolecular weight 357.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10474
Actions Inhibitor
M. Wt 357.79
Formula C19H16ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 53-86-1
Synonyms Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

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