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  1. Integrin inhibitor

    Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
  2. Integrin inhibitor

    Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
  3. Integrin Inhibitor

    A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 value of 20 nM and 25 nM, respectively.
  4. αvβ3 integrin inhibitor

    Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
  5. lpha-2-integrin inhibitor

    E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
  6. Inhibits integrin binding to RGD motifs

    RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
  7. Integrin inhibitor

    Cyclo(RGDyK) trifluoroacetate is a potent and selective alphaVbeta3 integrin inhibitor with IC50 of 20 nM.
  8. αV integrins inhibitor

    CWHM 12 can suppress all 5 alpha V integrins. CWHM12 not only worked the same way to prevent fibrosis as the genetic deletion method, it also prevent the progression of existing fibrosis in the liver and lungs and reversed some of the damage caused by fibrosis to those organs.
  9. α4β1/α9β1 inhibitor

    R-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor.
  10. α1β1 inhibitor

    Highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma; blocks human melanoma growth in nude mice.
  11. Integrin Inhibitor

    TCS2314 is a integrin very late antigen-4 (VLA-4; α4β1) antagonist with IC50 value of 4.4 nM.
  12. α2β1 integrin inhibitor

    BTT-3033 is a α2β1 integrin inhibitor.
  13. α9β1/α4β1 integrin inhibitor

    BOP sodium salt is a novel dual alpha9beta1/alpha4beta1 integrin inhibitor.
  14. VLA-4 inhibitor

    BIO-5192 is a small molecule VLA-4 inhibitor.
  15. LFA-1 inhibitor

    RWJ 50271 is a selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1).
  16. Integrin alpha4beta1 inhibitor

    BIO-1211 is an integrin alpha4beta1 inhibitor.
  17. LFA-1/ICAM-1 interaction inhibitor

    A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction with IC50 valueof 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion, respectively.
  18. αVβ3 integrin inhibitor

    Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
  19. α4 integrin receptor inhibitor

    Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.
  20. integrin-ligand interactions inhibitor

    RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation.

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