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HSP90 inhibitor

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Catalog No. A11272
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Availability: Out of stock

Product Name Catalog No. Price
IPI-493 1mg A11272-1
IPI-493 2mg A11272-2
IPI-493 5mg A11272-5
IPI-493 10mg A11272-10

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM.


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Chemical Information

Catalog Num A11272
Actions Inhibitor
M. Wt 545.62
Formula C28H39N3O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 64202-81-9
Synonyms IPI493; IPI 493; NSC 255109;17-Aminogeldanamycin;17-Amino Geldanamycin;17-Aminodemethoxygeldanamycin;17-Amino-17-demethoxygeldanamycin;
SMILES C[[email protected]]1C[[email protected]]([[email protected]]([[email protected]@H](/C=C(/[[email protected]]([[email protected]@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)N)/C)OC)OC(=O)N)\C)C)O)OC

Biological Activity

IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.33 mL 91.64 mL 183.28mL
0.5 mM 3.67 mL 18.33 mL 36.66 mL
1 mM 1.83 mL 9.16 mL 18.33 mL
5 mM 0.37 mL 1.83 mL 3.67 mL

*The above data is based on the productmolecular weight 545.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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