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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11272 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 545.62 |
| Formula | C28H39N3O8 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 64202-81-9 |
| Synonyms | IPI493; IPI 493; NSC 255109;17-Aminogeldanamycin;17-Amino Geldanamycin;17-Aminodemethoxygeldanamycin;17-Amino-17-demethoxygeldanamycin; |
| SMILES | C[[email protected]]1C[[email protected]]([[email protected]]([[email protected]@H](/C=C(/[[email protected]]([[email protected]@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)N)/C)OC)OC(=O)N)\C)C)O)OC |
Description |
IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.33 mL | 91.64 mL | 183.28mL |
| 0.5 mM | 3.67 mL | 18.33 mL | 36.66 mL |
| 1 mM | 1.83 mL | 9.16 mL | 18.33 mL |
| 5 mM | 0.37 mL | 1.83 mL | 3.67 mL |
*The above data is based on the productmolecular weight 545.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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