ISRIB (trans-isomer)

Catalog No.: A13816
PERK inhibitor
ISRIB (trans-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects of eIF2α phosphorylation.
Grouped product items
Product Name Price Stock Qty
ISRIB (trans-isomer) 10mg
$90.00
In stock
ISRIB (trans-isomer) 25mg
$180.00
In stock
ISRIB (trans-isomer) 50mg
$320.00
In stock
ISRIB (trans-isomer) 100mg
$520.00
In stock
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Biological Activity
Discription ISRIB (trans-isomer) is a potent and selective small molecule inhibitor of PERK signaling (IC50 ~5 nM) that can potently reverse the effects of eIF2α phosphorylation.
Product Information
Catalog Num A13816
Formula C22H24Cl2N2O4
Molecular Weight 451.34
SMILES O=C(N[C@@H]1CC[C@@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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