ITD-1

Catalog No.: A12924

TGF-β inhibitor

ITD-1

ITD-1 Chemical Structure

CAS NO. 1099644-42-4

ITD-1 is a novel and highly selective TGFβ pathway inhibitor. ITD-1 molecule turns stem cells into heart cells.

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5 mg
$60.00
10 mg
$80.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • M. C. Wilkes, .et al. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase, Nat Commun, 2020, 11: 3344 PMID: 32620751

Biological Activity

ITD-1 is a novel and highly selective TGFβ pathway inhibitor. ITD-1 molecule turns stem cells into heart cells.
In vitro DMSO 76 mg/mL (182.89 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.33 mL 240.66 mL
0.5 mM 4.81 mL 24.07 mL 48.13 mL
1 mM 2.41 mL 12.03 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12924
Actions Inhibitor
CAS No. 1099644-42-4
Formula C27H29NO3
M. Wt 415.52
Purity >98%
SMILES O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=C(C4=CC=CC=C4)C=C3)OCC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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