JANEX-1

Catalog No.: A15134

JAK3 inhibitor

JANEX-1

JANEX-1 Chemical Structure

CAS NO. 202475-60-3

Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 uM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $95.00

Special Price $85.50

10 mg

Regular Price: $165.00

Special Price $148.50

25 mg

Regular Price: $375.00

Special Price $337.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (IC50 = 78 uM); has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.63 mL 168.17 mL 336.35 mL
0.5 mM 6.73 mL 33.63 mL 67.27 mL
1 mM 3.36 mL 16.82 mL 33.63 mL
5 mM 0.67 mL 3.36 mL 6.73 mL

*The above data is based on the productmolecular weight 297.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15134
Actions Inhibitor
M. Wt 297.31
Formula C16H15N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 202475-60-3
Synonyms WHI-P131, Janex 1, WHI-P 131
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC

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