Total item
Cart Subtotal
$0.00 Biological Activity
JNJ-28312141 is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.71 mL | 108.56 mL | 217.12 mL |
| 0.5 mM | 4.34 mL | 21.71 mL | 43.42 mL |
| 1 mM | 2.17 mL | 10.86 mL | 21.71 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.34 mL |
*The above data is based on the productmolecular weight 460.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12687 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 885692-52-4 |
| Formula | C26H32N6O2 |
| M. Wt | 460.57 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | JNJ 28312141, JNJ28312141 |
| SMILES | CN(C)CC(=O)N1CCC(CC1)C2=CC(=C(C=C2)NC(=O)C3=NC=C(N3)C#N)C4=CCCCC4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy JNJ-28312141 | JNJ-28312141 Supplier | purchase | cost | manufacturer | order | distributor | buy 885692-52-4| 885692-52-4 Supplier | purchase 885692-52-4 | 885692-52-4 cost | 885692-52-4 manufacturer | order 885692-52-4 | 885692-52-4 distributor
Adooq Quality Guarantee
We promise all products perform as described.